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T1 Diabetes Features
T1 Diabetes Features

● Progression to insulin within 3 years
● BMI (< 25 for sens/spec*)
● Age at diagnosis
● Weight loss
● Diagnosis HbA1c (>115 mmol/mol)  ● Diagnosis Glucose (>20mmol/L)
● Lack of FH diabetes
● Osmotic symptoms 
● DKA
● Other autoimmune disease

● Progression to insulin within 3 yea...
(< 30 for sens/spec*
other guidelines < 35)
(< 30 for sens/spec*...
T1/T2 Prediction Model
T1/T2 Prediction Model
T2 Diabetes Features
T2 Diabetes Features

● BMI at diagnosis > 25
● Absence of weight loss
● Absence of Ketoacidosis
● Less marked hyperglycaemia
● Weak discriminators 
- Non-white ethnicity - Family history of Diabetes - Longer duration/mild severity of symptoms prior to presentation - Features of metobolic syndrome - No Fhx of autoimmunity

● BMI at diagnosis > 25...
MODY Features
MODY Features

● Age < 35 
● HbA1c < 58 mmol/mol at diagnosis
● Parent with Diabetes
● Features of a specific monogenic cause (e.g., renal cysts, partial lipodystrophy, maternally inherited deafness, and severe insulin resistance in the absence of obesity)
● Monogenic diabetes prediction model probability >5%

● Age < 35...
ADA 2024
ADA 2024
ABCD
ABCD
Diabetes Classification
Diabetes Classification
ADA 2024
ADA 2024
ADA 2024
ADA 2024
*Exeter 
*Exeter 
AABBCC approach
AABBCC approach
MODY calculator
MODY calculator
NHS testing criteria
NHS testing criteria
ADA Flowchart
ADA Flowchart
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